Prof. Dr. Basil Thanopoulos

Prof. Dr. Basil Thanopoulos

Medic Primar Cardiolog

Cardiologie intervențională

Director Interventional Pediatric Cardiology, Iatricon Medical Center, Athens, Greece Proctor în proceduri minim invazive de terapia malformațiilor congenitale cardiace Medic în cadrul Secției Destinată Terapiei Minim Invazive a Malformațiilor Congenitale Cardiace



Present Status: Director, Interventional Pediatric Cardiology, Iatricon Medical Center, Athens, Greece



1961-1967: Student of medical school, Athens University.

1967: Master’s degree-Medical School University of Athens.

1973: Specialty of Pediatrics.

1973: ECFMG certificate.

1973: Scholarship from LA. California USA Cardiological Society for specialization in pediatric cardiology at Torrance hospital, UCLA affiliated.

1975-1977: Instructor of Pediatrics, Medical School of University of Illinois, Chicago, USA.

1976-1977: Research associate of Pediatrics (Pediatric Cardiology) – Teaching Associate of Pharmacology, Medical School University of Illinois, Chicago, USA.

1977: FLEX Certificate a. State of Illinois

b. State of California, USA.

1977: Clinical Assistant Professor of Pediatrics (Pediatric Cardiology) Medical School University of San Diego, California, USA.

1980-1984: Honorary Assistant Professor of Pediatrics, Medical School University of Patras, Greece.

1988-1990: Associate Professor of Pediatrics (Pediatric Cardiology) Medical School University of Patras, Greece.

1992: Visiting Professor Belgrade School of Medicine, Yugoslavia.

1994: Foreign member of Serbian Academy of Science and Arts.

1997: Honorary Consultant Royal Brompton Hospital, London.

1999: Professor of Pediatric Cardiology, Yerevan Medical State Unversity, Yerevan, Armenia.


1969-1970: General practitioner in a rural Medical Clinic sponsored by the Greek Ministry of Health.

1970-1971: Resident in Internal Medicine, General Hospital of Piraeas, Greece.

1971-1973: Resident in Pediatrics, General Hospital of Piraeas, Greece.

1973-1974: Fellow in Pediatric Cardiology, Torrance Hospital (UCLA affiliated), California, USA.

1974-1975: Fellow in Pediatric Cardiology, Cook County Hospital, Chicago, Illinois, USA.

1975-1976: Fellow in Pediatric Cardiology, University of Illinois Hospital, Chicago, Illinois – USA.

1976-1977:Research Associate- Senior Registrar of Pediatric Cardiology and Student of Cardiovascular Pharmacology in Postgraduate School (PhD level), University of Illinois, Chicago, USA.

Test results: Pharmacology (A), Physiology (B), PhD educational program has been suspended after the first year due to undertaking an Assistant Professor’s post at University of San Diego, California, USA.

1977: Clinical assistant Professor of Pediatric Cardiology, University of San Diego Hospital, San Diego, California, USA.

1977: Senior Resistrar of Pediatric Clinic and Cardiac Catheterization Laboratory of General Hospital of Piraeus “Saint Panteleimon”, Nikea, Piraeus Greece.


1984-85: Consultant Pediatric Cardiologist – Neonate Section of “Alexandra” Maternity Hospital.

1986-2009: Director of Pediatric Cardiology Department and of Hemodynamiic Laboratory of “Agia Sophia” Children’s Hospital, Athens, Greece.

2009- :Director Interventional Pediatric Cardiology, Iatricon Medical Center, Athens, Greece

Membership in scientific societies


1.Hellenic Society of Pediatrics (ordinary member)

2.Hellenic Society of Perinatol medicine (ordinary member)

3.Hellenic Society of Cardiology (ordinary member)

a.Working group for hemodynamic and invasive cardiology (ordinary member).

b.Working group for echocardiography (ordinary member)

c.Working group for congenital heart disease (Member – President: 1990).

d.Hellenic College of Cardiology – (General secretary 2002-).


1.European association of Pediatric Cardiologists (ordinary member – representative of the Association for Greece (2000-2005).

2.American College of Cardiology (Congenital Heart Disease and Pediatric Cardiology section).

3.Balkanian society of Pediatric Cardiology and Cardiosurgery (vice President since 1998).

4.Turkish society of Pediatric Cardiology (honorary member).

5.European society of Cardiology. Adult congenital heart disease. (ordinary member)


a.Greek journals

1.Hellenic Journal of Cardiology

Member of the editorial board since 1997

2.Pediatrics (reviewer).

b.International journals

1.European society of Cardiology ( Abstract reviewer 1998 -2003)

2.European society of Pediatric Cardiology (Abstract reviewer since 2002)

3.Catheterization and Cardiovascular Interventions

4.Journal of American College of Cardiology


6.European journal of Echocardiography.

7.Nature Clinical Practice Cardiovascular Medicine

8.Journal of International Cardiology


Peer review journals (indexed Medline)

1.Ikkou D., Thanopoulos B., Ikkos D.G.: 24 hours plasma levels of growth hormones in growth retardation of children with congenital heart disease.

Helv. Pediatr. Acta 28:583-588, 1974.

2.Thanopoulos B., Ikkou D., Millingos M., Foutakis D.: Cardiorespiratory syndrome due to enlarged tonsils and adenoids.

Acta Pediatr. Scand. 64:659-663, 1975.

3.Leake R.D., Thanopoulos B., Nieborg R.: Hyperviscosity syndrome associated with necrotizing enterocolitis.

Amer. J Dis. Child. 129:1192-1194, 1975.

4.Emmanouilides G.C., Thanopoulos B., Siassi B., Fisbein M.: Agenesis of ductus arteriosus associated with the syndrome of tetralogy of Fallot and absent pulmonary valve.

Amer. J. Cardiol. 37:403-409, 1976.

5.Thanopoulos B., Fisher E., Dubrow I., Hastreiter A.: Right and left ventricular volume characteristics in common atrioventricular canal. Circulation 57:991-995, 1978.

6.Thanopoulos B., Pahlajani D., Serrato M.: Silent common A.V. canal with large left to right shunt. Pan. Med. 20:151-154, 1978.

7.Thanopoulos B., Dubrow I., Fisher E., Hastreiter A.: Double outlet right ventricle with subvalvular aortic stenosis. Br. Heart J. 41:241-244, 1979.

8.Fisher E., Thanopoulos B., Eckher F.A., Hastreiter A., Dubrow I.W. Pulmonary atresia with obstructed ventricular septal defect. Ped. Cardiol. 1:209-217, 1980.

9.Zeis P.M., Thanopoulos B., Pietroutsakos I.N., Koukoutsakis P.M.: Complete artioventricular block associated with propranolol therapy. J. Pediat. 98:327, 1981.

10.Drossos Ch., Thanopoulos B., Papadimitriou Th., Millingos M., Papadimitriou A., Konstantellou Evang., Ikkou D.: Incidence of anaemia in congenital heart disease.

La Pediatr. 3:309-312, 1981.

11.Thanopoulos B., Frimas C.: Partial splenic embolization in the treatment of hypersplenism secondary to Gaucher disease.

J Pediatr. 101:740-743, 1982.

12.Malamitsi Puchner A., Thanopoulos B., Christoforaki M., Konstantellou Evang., Papathoma Eug., Simbruner G.: Digoxin levels in the serum of healthy neonates.

Eur. J. of Pediat. 145:314-315, 1986.

13.Thanopoulos B., Fisher E., Hastreiter A.: Large ductus arteriosus and intact ventricular septum associated with congenital absence of the pulmonary valve.

Br. Heart J. 55:602-604, 1986.

14.Mantagos S., Frimas C., Thanopoulos B., Beratis N.: Fructose 1.6 diphosphetase deficiency presenting as Reye like syndrome.

J. Pediatr. Endocrinol. 2:131-134, 1987.

16. Thanopoulos B., Andreou A., Frimas C.: Prostagladin E2 administration in infants with ductus – dependent cyanotic congenital heart disease.

Eur. J. Pediat. 146:279-282, 1987.

17.Thanopoulos B., Frimas C., Mantagos S., Beratis N.: Gaucher disease: Treatment of hypersplenism with splenic embolization.

Acta Pediat. Scand. 76:1003-1007, 1987.

18.Thanopoulos B.D., Margetakis A., Papadopoulos G., Kefalakis E., Rokas S.: Valvuloplasty with large trefoil balloons for the treatment of congenital pulmonary stenosis.

Acta Pediat. Scand. 78:742-746, 1989.

19.Thanopoulos B.D., Rokas S., Frimas C.A., Mantagos S.P., Beratis N.G.: Cardiac involvement in postnatal rubella.

Acta Pediat. Scand. 78:141-144, 1989.

20.Sideris E.B., Sideris S.E., Thanopoulos B.D., Ehly R.L., Fowlkes J.P.: Transvenous atrial septal defect occlusion by the buttoned device: Application and follow-up in children: Early experience.

Am J Cardiol. 66:1524-1526, 1990.

21.Thanopoulos B.D., Georgakopoulos D., Tsaousis G.S., Simeunovic S.: Percutaneous balloon dilation of the atrial septum immediate and midterm results.

Heart 76:502-506, 1996.

22.Thanopoulos B.D., Georgakopoulos D., Tsaousis G.S., Triposkiadis F., Paphitis C.A.: Percutaneous balloon pericardiotomy for the treatment of large, non – malignment pericardial effusions in children.

Cath. Cardiovasc. Diagn. 40:289-291, 1997.

23.Thanopoulos B.D., Triposkiadis F., Tsaousis G.S.: Single – stage balloon valvuloplasty for critical pulmonary valve stenosis in the neonate.

Cath. Cardiovasc. Diagn. 40:322-325, 1997.

24.Thanopoulos B.D., Triposkiadis F., Margetakis A., Mullins C.E.: Long segment coarcatation of the aorta treatment with multiple balloon – expandable stent implantation.

Am Heart J 133:470-473, 1997.

25.Masura J., Walsh K.P., Thanopoulos B.D., Chan C., Bass J., Goussous Y., Gavora P., Hizazi Z.H.: Catheter closure of moderate – to large – sized patent ductus arteriosus using the new Amplatzer Duct Occluder: Immediate and sort – term results.

J Am Col Cardiol 31: 878-882, 1998.

26. Thanopoulos B.D., Laskari C.V., Tsaousis G.S., Zarayelyan A., Vekiou A., Papadopoulos G.S.: Closure of atrial septal defects with the Amplatzer Occluder device: Preliminary results.

J Am Col Cardiol 31:1110-1116, 1998.

27. Brierley J.J., Reddy T.D., Rigby M.L., Thanopoulos V.D., Redington A.N.: Traumatic damage to the mitral valve during percutaneous balloon valvotomy for critical aortic stenosis.

Heart 79:200-202, 1998.

28. C.J.Trapali, B.D.Thanopoulos: Severe right ventricular dysfunction in a neonate with aortic origin of the RPA.

Pediatric Cardiology 19:425-427, 1998.

29. Thanopoulos B.D., Tsaousis G.S., Konstadopoulou G.N., Zarayelyan A.: Transcatheter closure of muscular ventricular septal defects with the Amplazer Ventricular Septal Occluder. Initial clinical applications in children.

J Am Col Cardiol 33:1395-1399, 1999.

30. Dhillon R., Thanopoulos B.D., Tsaousis G.S., Tripaskiadis F., Kiriakides M., Redington A.: Transcatheter closure of atrial septal defects in adults with the Amplatzer septal occluder.

Heart 82:559-564, 1999.

31. Thanopoulos B.D., Hakim F.A., Hiari A., Goussous Y., Basta E., Zarayelyan A.A., Tsaousis G.S.: Further experience with Transcatheter closure of the Patent Ductus Arteriosus using the Amplatzer Duct Occluder.

J Am Coll Cardiol 35:1016, 2000.

32. Thanopoulos B.D., Hadjinikolaou G., Tsaousis G.S., Triposkiadis F., Spirou P.: Stent treatment for coarctation of the aorta: intermediate term follow up and technical considerations.

Heart 84 (1):65-70, 2000.

33. Briasoulis G., Papadopoulos G., Zavras N., Pailopoulos V., Hatzis T., Thanopoulos V.: Cardiac troponin I in Fulminant adenovirus myocarditis treated with 24 – infusion of high – dose intravenous immunoglobulin.

Pediatr Cardiology 21 (4):391-394, 2000.

34. Papadopoulos G.S., Eleftherakis N.G., Thanopoulos B.D.: Cardiac tambonade in a child with ascariasis. Cardiol Young 10 (5):539-541, 2000.

35. Tsilimigaki A., Maraka S., Tsekoura T., Agelakou V., Vekiou A., Paphitis C., Thanopoulos V.: Eighteen month’s experience with remote diagnosis, management and education in congenital heart disease.

J Telemed Telecare 7 (4):239-243, 2001.

36. Thanopoulos B.D., Hakim F.A., Hiari A., Tsaousis G.S., Paphitis C., Hijazi Z.M.: Patent ductus arteriosus equipment and technique. Amplatzer duct occluder: intermediate – term. Follow – up and technical considerations.

J Interv Cardiol 14:247-254, 2001.

37. Thanopoulos B (V)D., Tsaousis G.S., Djukie M., Al Hakim F., Eleftherakis N.G., Simeunovic S.D.: Trascatheter closure of High Pulmonary Artery Pressure Patent Ductus Arteriosus with the Amplatzer Muscular Ventricular Septal Defect Occluder.

Heart 87:1-3, 2002.

38. Thanopoulos B (V)D., Georgakopoulos DJ., Tsaousis G.S., Eleftherakis N.G.: A Novel use of the Amplatzer Muscular Ventricular Septal Defect Occluder.

Cathet Cardiovasc Interven, 14:234-7, 2002.

39. Triposkiadis F., Ghiokas S., Skoularikis I., Kotsakis A., Giannakoulis I., Thanopoulos B.D.: Cardiac adaptation to intensive training in prepubertal swimmers.

Eur J Clin Invest, 32:16-23, 2002.

41. Thanopoulos B.D., Tsaousis G.S., Karanassios E.S., Eleftherakis N.G., Paphitis C.: Transcatheter closure of Perimembranous Ventricular Septal Defect with the Amplatzer Asymmetric Ventricular Septal Defect Occluder. Preliminary experience in children.

Heart, 89:918-22, 2003.

42. Thanopoulos B.D., Karanassios E., Tsaousis G.S., Papadopoulos G.S., Stefanadis C.: Catheter Closure of Congenital/Acquired Muscular VSDs and Perimembranous VSDs using the Amplatzer Devices.

J Interv Cardiol, 16:399-407, 2003.

43. Bass J.L., Karla G.S., Arora R., Masura J., Gavora P., Thanopoulos B.D., Torres W., Sievent H., Carminari M., Fisher G., Ewert P.: Initial human experience with the Amplatzer perimembranous ventricular septal occluder device.

Cathet Cardiovasc Interv, 58:238-45, 2003.

44. Thanopoulos B.D.: Catheter Closure of Perimembranous/Membranous Ventricular Septal Defects Using the Amplatzer Occluder Device.

Pediatr Cardiol. 2004 May 12 (Epub ahead of print).

45. Thanopoulos B.D., Rigby M.L.: Outcome of transcatheter closure of muscular ventricular septal defects with the Amplatzer ventricular septal defect occluder.

Heart 2005 ; 91 (4):513-6.

46.Papadopoulou D.I., Yakoumakis E.N., Makri T.K., Sandilos P.H., Thanopoulos B.D., Georgiou E.K.: Assessment of patiet radiation doses during transcatheter closure of ventricular and atrial septal defects with Amplatzer devices.

Catheter Cardiovasc Interv. 2005 ; 65:434-41.

47.Papadopoulou D.I., Yakoumakis E.N., Makri T.K., Sandilos P.H., Thanopoulos B.D., Georgiou E.K., Houndas D, Yakoumakis N, Georgiou E. : Entrance radiation dose during pediatric cardiac catheterizations performed for diagnosis or treatment of congenital heart disease.

Radiat Prot Dosimetry, 2005; 117: 236-40

48. Vavuranakis M, Tzannos KA, Thanopoulos BD, Vlasis K, Stefanadis C.

Severe hemolysis complicating transcatheter occlusion of a patent ductus arteriosus: the importance of elimination of residual flow.

Hellenic J Cardiol. 2007; 48: 373-376.

49. Thanopoulos BV, Eleftherakis N, Tzanos K, Skoularigis I, Triposkiadis F.: Stent implantation for adult aortic coarctation.

J Am Coll Cardiol. 2008 ;52:1815-6.

50. Thanopoulos BV, Tzannos KA, Eleptherakis N, Stefanadis C.:

Comparison and results of transcatheter closure of patent ductus arteriosus using the swivel-disk device versus plug occluder in children.

Am J Cardiol. 2008 Aug 15;102(4):486-90. Epub 2008 May 22.

51. Loukopoulou SN, Eleptherakis NG, Kourtesis AN, Thanopoulos D.: Combined epicardial and transvenous pacing in an infant with operated complex congenital heart disease and permanent epicardial DDD pacemaker as treatment of epicardial lead. Hellenic J Cardiol. 2009; 50: 68-72.

52. Thanopoulos B, Eleptherakis N, Tzannos K, Stefanadis Ch.: Transcatheter closure of patent ductus arteriosus usig the new Amplatzer duct occluder.:initial clinical applications in children. Am Heart J 2008; 156: 917e-917e6.

53. Further experience with catheter closure of patent ductus arteriosus usig the new Amplatzer duct occluder in children. Am J Cardiol 2010; 105:1005-9.

54. Thanopoulos BV, Douskou M, Giannakoulas G.: Multislice computed tomography after stent implantation for aortic coarctation. Eur Heart J 2010; May 28. (Eub ahead of print).

55. Zanjani KS, Thanopoulos BD, Peirone A, Alday L, Giannakoulas G.:

Usefulness of stenting in aortic coarctation in patients with the Turner

syndrome. Am J Cardiol (accepted for publication-2010.)

56. Dardas PS, Ninios VN, Mezilis NE, Tsikaderis DD, Thanopoulos VD.: Percutaneous closure of atrial septal defects: immediate and mid-term results. Hellenic J Cardiol 2010; 51: 104-12

57. Thanopoulos BD, NiniosV, Germanakis J.: Catheter Closure of a Right Aortico-Atrial Tunnel in a Patient 4-Year Old. JACC Interv 2013; 6: (1).e 1-2.

58. Chamakou ACDede EMoutafi AThanopoulos VChryssanthopoulos SLoukopoulou SPitsavos C,Stefanadis CDavos CH.: Neurohormonal and cytokine fluctuations following transcatheter closure for an atrial septal defect. JIC 2012; 57: 130-5.

59. Thanopoulos BD. Giannakoulas G,. Arampatzis C.A,: Percutaneous Pulmonary Valve Implantation in the Native Right Ventricular Outflow Tract

CCI 2012; 57: 427-9.

60. Thanopoulos BD et al Int JCardiol 2013, May 25(Epub ahead of print).

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